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Clinical Remission With Biologic Use Among US Subspecialist-Treated Patients With Severe Asthma: Results From the CHRONICLE Study

Rationale: There are limited real-world data regarding the proportion of patients with severe asthma (SA) who achieve clinical remission with biologic treatment. Methods: CHRONICLE is an observational study of subspecialist-treated adults with SA. Sites report exacerbations and biologic use from 12 months prior to enrollment forward. Monthly Asthma Control Test (ACT) scores and 6-monthly specialist assessments of asthma control are collected. Clinical remission was... Read More

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Mobile Health Technology and Pain Management

The modernization of healthcare is critical to all clinicians, especially those who treat patients with chronic pain. Preliminary data suggests that mHealth technology can improve treatment plan adherence, medication protocol compliance and lead to improved patient outcomes. The mHealth platform described bridges a treatment gap that occurs between visits and has been demonstrated to improve clinically important outcomes. Improving physician-patient communication in... Read More

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Assessment of Clinical Response to Narcolepsy Treatment: Challenges and Best Practices

Narcolepsy is a chronic neurological disorder characterized by excessive daytime sleepiness, cataplexy, and other REM-dissociative features. Assessment of treatment response requires evaluating multiple domains that include narcolepsy symptoms, comorbid psychiatric conditions (e.g., anxiety, depression, ADHD), quality of life, and medication side effects. Existing scales may be insufficient to capture the dynamic and personalized changes that occur visit by visit... Read More

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Introduction to TheResearchPost: A New Approach to Peer-reviewed Medical Publishing

TheResearchPost is a start-up, open-access, peer-reviewed, medical journal built on a data visualization platform. The journal is designed for medical research, including clinical and preclinical research, real-world evidence, health economics and outcomes research, observational studies, and clinical case studies. The journal's format features slides instead of manuscripts, which streamlines the writing and review process, and better matches how people read and share... Read More

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